Possible serious bacterial infections (PSBI), or sepsis, accounts for 23 percent of newborn deaths in low and middle income countries.1,2 The “gold standard” treatment – hospitalization and 7-10 days of injectable antibiotics – is often not feasible in low resource settings. In 2007, the Health Research Program and partners convened a global consultation to review evidence on home-based therapies for PSBI treatment. Experts determined there was insufficient evidence to recommend home-based treatment and that further research was needed.
The Accelovate Project (2011-2016) increased the availability and use of life-saving technologies in low resource settings to accelerate reductions in mortality and morbidity. Accelovate was implemented by Jhpiego in partnership with the Johns Hopkins University Center for Bioengineering Innovation and Design, the Johns Hopkins University Center for Global Health, and Population Services International.
CIRCLE provides technical, logistical, and administrative support to the USAID Health Research Program. The goal of the project is to coordinate and support research-to-use activities to improve health outcomes and increase survival of newborns, children, and women.