Our previous blog introduced you to the fundamentals of Developmental Evaluation (DE) and to the USAID Coordinating Implementation Research to Communicate Learning and Evidence (CIRCLE) Project, which is carrying out a Developmental Evaluation of Boresha Afya, an integrated health services delivery initiative in Tanzania. This installment describes the start-up phase of the CIRCLE DE of Boresha Afya and highlights important steps for setting up a DE that can be applied to most contexts.